Browsing by Subject "A61K 38/12"

Now showing items 1-7 of 7

    • Engineering the production of a conformational variant of occidiofungin that has enhanced inhibitory activity against fungal species 
      Smith, James Leif; Ravichandran, Akshaya; Lu, Shien; Gu, Ganyu (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2017-04-18)
      Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of ...
    • Methods for the treatment of depression and anxiety by a melanocortin 5 receptor antagonist, PG-20N 
      Hruby, Victor J.; Cai, Minying; Morgan, Caurnel (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2020-05-19)
      Compositions and methods for treating a depressive disorder or an anxiety disorder in a subject in need of such treatment are described. A therapeutically effective amount of a composition comprising compound PG-20N in a ...
    • Modulators Of Melanocortin Receptors For The Treatment Of Depression And Anxiety 
      Hruby, Victor J.; Cai, Minying; Morgan, Caurnel (United States. Patent and Trademark Office; Texas A&M University. Libraries, 1/3/2023)
      Compositions and methods for treating a depressive disorder or an anxiety disorder in a subject in need of such treatment are described herein. A therapeutically effective amount of a composition comprising a melanocortin ...
    • Occidiofungin formations and uses thereof 
      Smith, James L.; Pruett, Stephen; Austin, Frank; Lu, Shien; Akshaya, Ravichandran; Laihing, Steven (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2019-04-23)
      Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of ...
    • Replacement therapy for dental caries 
      Hillman, Jeffrey D.; Smith, James Leif; Wilson-stanford, Shawanda R. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2016-02-16)
      The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental ...
    • Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features 
      Hillman, Jeffrey D.; Smith, James Leif; Wilson-Stanford, Shawanda R. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2018-05-08)
      The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics ...
    • β-turn peptidomimetic cyclic compounds 
      Saragovi, Horacio Uri; Burgess, Kevin (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2005-04-19)
      Proteolytically stable small molecule β-turn peptidomimetic compounds have been identified as agonists or antagonists of neurotrophin receptors, such as TrkA. A compound of particular interest binds the immunoglobulin-like ...